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A new equivalence based metric for predictive check to qualify mixed-effects models
2005
AAPS Journal
The main objective of any modeling exercise is to provide a rationale for effective decision making during drug development. The aim of the current simulation experiment was to evaluate the properties of predictive check as a covariate model qualification technique and, more importantly, to introduce and evaluate alternative criteria to qualify models.
doi:10.1208/aapsj070353
pmid:16353930
pmcid:PMC2751255
fatcat:jr73xzb3ubdwnm44nbvlab2wg4