The study examined the effect of Delonix regia (flame tree) as biorodenticide in eliminating Wister albino rat. The plant samples used were collected from the Nnamdi Azikiwe university campus, dried for three days then the extract was extracted with the use of Soxhlet extractor using ethanol as extraction solvent after which the extract was concentrated in a rotary evaporator. The extract was administered to the wister Albino rate ate 200mg/ml dose and 400mg/ml dose. From the phytochemical

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... sis of the plant, the result showed that the plant contains phytochemicals such as steroids, alkaloid among others. The result also showed that the weight of the rat increased to 128.33±7.53 b when given treatment as compared to their body weight(114.66±8.08 a ) before treatment. The result further indicated that at 200mg/ml, the weight of the rat is statistically significant than that at 400mg/ml. From the analysis, it was noted that the organ weight of the rat and PCV of 200mg/ml dosage is higher (43.66±4.48 b ) than that 400mg/ml (30.33±2.603 a ) though this result is not statistically significant at P>0.05%. Comparing the relative organ weight of the rat at 200mg/ml and at 400mg/ml, the weight at 400mg/ml for liver(3.68%) and kidney(0.79%) is higher than 200mg/ml relative liver weight(3.55%) and kidney(0.65%). The difference in the relative organ weight is also not statistically significant at P>0.05%. There were no toxicity effects of the extract observed on the rat neither were there any mortality. Therefore, the study recommended that pharmaceutical industries should harness the potential of Delonix regia extract in the production of drugs and use it in the control of obesity among the human population and little dosage of the Delonix regia extract can be also be used in others to boast and maintain packed cell volume.