Apparatus used in Manufacturing in Connection with the Prescription Department**Read before Section on Practical Pharmacy and Dispensing, A. Ph. A., Cleveland meeting, 1922

Crosby B. Washburne
1922 The Journal of the American Pharmaceutical Association (1912)  
Sept. 1922 AMERICAN PHARMACEUTICAL ASSOCIATION 703 the next morning, after it has regained room temperature. The graduate ia standardized for 60' F., but this makes no difference, as the subsequent measuring is made with graduates and medicine glasses similarly standardized. Making trial solutions in a 100-mil flask marked at 25' C. gave the following weights a t the temperature recorded: A, 170.05, at 24" C.; B, 167.206, at 27" C.; C, 169.69, at 29' C. The flask was marked to hold 99.604 Gm.
more » ... freshly distilled water a t 2 5 O C., no correction for atmospheric pressure, weighed on a box prescription scale. Whenever a freshly made solution shows the slightest discoloration it is cleared with a few particles of sodium thiosulphate, which quickly clear it, and, this is also done at any time the solution develops color. The sample of highly discolored solution will be cleared before you to show how little thiosulphate it takes and how quickly it is done.' Since the dose of thiosulphate may be from 1 to 4 Gm., this small amount can do no harm, neither should the sodium iodide thus introduced into the solution make any difference. -This solution usually remains undiscolored in our shop bottle for more than several months, but when it does not, the "cleared" solution usually keeps well. From the few data submitted, it is evident that this solution closely approximates the theoretical saturated solution, and can be dispensed as such. In my experience, this solution has been singularly free from portions of the salt crystallizing out from solution. In conclusion I would urge the dispensing of this solution of definite strength instead of the indefinite so-called saturated solutions, usually extemporaneously made. This paper will discuss the installation of machinery used in manufacturing in connection with the prescription department of a retail drug store. The problem in this case is of necessity somewhat different from that relating to machinery used for similar purposes in large manufacturing institutions. The apparatus necessary is that which will assist in mixing powders; mixing liquids; compressing suppositories; grinding substances of different nature, such as hard crystalline substances, and unctuous substances such as cacao butter. The powder mixer can be made of any size from twenty-five to two hundred pounds, capacity to suit the demands of the particular requirement. The one which we have in operation is about a one hundred and fifty pound mixer and is made as follows: A rectangular box, with square ends measuring two feet and the length of the box being four feet, is covered with cloth resembling court plaster, which is tightly glued down to prevent sifting. It is swung from the center by short shafts * Read before Section on Practical Pharmacy and Dispensing, A. Ph. A., Cleveland meeting, 1922.
doi:10.1002/jps.3080110909 fatcat:j3zvaf5vdvh35h4z7ivgyg2hpy