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The surface cholesteryl ester content of donor and acceptor particles regulates CETP
2003
Journal of Lipid Research
Cholesteryl ester transfer protein (CETP) activity is regulated, in part, by lipoprotein composition. We previously demonstrated that CETP activity follows saturation kinetics as cholesteryl ester (CE) levels in the phospholipid surface of donor particles are increased. We propose here that the plateau of CETP activity occurs because the surface concentration of CE in the acceptor becomes rate limiting. This hypothesis was tested in CETP assays between synthetic liposomes whose CE content was
doi:10.1194/jlr.m300063-jlr200
pmid:12730298
fatcat:6gcui2b2d5ha3lk7opqzax5mpq