The relation between plasmatic triglycerides levels and polymorphisms -133T>C and 56C>G of ApoA5 codifying gene

Ismael San Mauro Martín, Ana María Ruiz León, Elena Garicano Vilar, Javier Andrés Blumenfeld Olivares, Eva Pérez Arruche, Esperanza Arce Delgado, María José Ciudad Cabañas, Luis Collado Yurrita
2016 Jounal of Negative and No Positive Results  
Aim. The aim was to evaluate the association between polymorphisms -113C>T (rs662799) and 56C>G (rs3135506) and plasmatic triglycerides levels in adults. Methods. A randomized clinical trial of 44 subjects from two hospital centers from Madrid (Spain). Anthropometric survey, blood test genetic analysis and an Ad hoc survey (lifestyle habits: nutrition, physical activity, sleep) were conducted. Results. No statistically significant differences were observed between polymorphism 113G>T or 56C>G
more » ... d plasmatic triglycerides concentrations (p>0.05). However, statistically significant differences were found between gene variant 56C>G and total cholesterol levels and low-density lipoproteins (p=0.015 and p=0.036, respectively). Conclusion. This trial brings to light no association between plasmatic triglycerides levels and polymorphic variants 56C>G and - 1131T>C of Apo5 coding gene.
doi:10.19230/jonnpr.2016.1.1.932 doaj:dcca249f77144fb7becb1937ef27bfee fatcat:ppqccl24grfsbcevz3xpmqwihi