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The antimalarial properties of crude extract and PITC-2 a compound isolated from tissue cultured plant Pluchea indica traditionally used medicine in various regions of India was evaluated for antimalarial property. The air-dried powdered plant part (roots) was extracted, sequentially with solvents of increased polarity (methanol, butanol, petroleum-ether, and ethyl-acetate). The extract was then administrated orally into albino mice infected with malarial parasites at dose of 100 and 300fatcat:5tjw6wrrf5g6hpci3lpqpyg63u