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Journal of Leukemia
Human endogenous retrovirus (HERVs) integrated in the human genome millions of years ago and became a stable part of the inherited genetic material. Most of these HERVs are dysfunctional due to numerous mutations and thus making it impossible to generate a full, infectious retrovirus particle from a single genetic locus. However, many HERVs are still exceptionally well preserved and maintain Open Reading Frames encoding functional viral proteins. The permanence of HERV´s genes along evolutiondoi:10.4172/2329-6917.1000217 fatcat:224dnlazwzfg7mt4f7pn6kwxwq