Porcine stress syndrome (PSS) and ryanodine receptor 1 (RYR1) gene mutation in European wild pig (Sus scrota ferus)

Jovanovic Slobodan, Trailovic Ruzica, Savic Mila, Sarac M.
2005 Acta Veterinaria  
Expression of the stress syndrome (PSS) in European wild pig was evaluated by Halothane test and tested animals were typed by PCR/RFLP test for C/T mutation at nt 1843 in RYR1 gene. A total of 56 animals, at the age of 5 months, weighing 20 kg average, were tested. Hal+ (MHS -malignant hyperthermia susceptible) phenotype was revealed in 6 pigs, 47 animals expressed Hal-(MHN -malignant hyperthermia resistant) phenotype, while 3 animals showed no response to administration of 3% halothane after 5
more » ... minutes and they were marked as Halr (halothane resistant) phenotypes. Genotyping of 56 wild pigs revealed that the tested population was homozygous for the normal C/C allele at RYR1 locus. The results obtained by halothane test show that expression of the PSS in wild pigs is modulated and influenced by factors other then RYR1 genotype.
doi:10.2298/avb0503251j fatcat:ujgdiw4a5jdclnabxinhcr4xx4