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People with histories of homelessness and serious mental illness experience profound health disparities. Housing First is an evidenced-based practice that is working to end homelessness for these individuals through a combination of permanent housing and community-based supports. Methods: The Jefferson Department of Family and Community Medicine and a Housing First agency, Pathways to Housing-PA, has formed a partnership to address multiple levels of health care needs for this group. We presentdoi:10.3122/jabfm.2013.03.120239 pmid:23657696 fatcat:335x6mbtubh3lbpj7czjnfj6xy