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Drug development is a time-consuming process from the start of research to obtaining approval, and the probability of success with a candidate compound is extremely low. We aim to understand the characteristics of the flow and localization of knowledge during drug development in the global pharmaceutical industry. We analyze the multilayer network constructed with the drug pipeline layer, global supply chain layer, and global ownership layer. First, we identify the bow-tie structure and thedoi:10.1007/s41109-020-00328-5 fatcat:dpnqutwfkbftherb25b6js2fvq