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ACTH Therapy in Epileptic Spasms without Hypsarrhythmia
2005
Pediatric Neurology Briefs
The efficacy of pyridoxal phosphate (PLP) compared to pyridoxine (PN) in the control of idiopathic intractable epilepsy was studied in 94 children, aged 8 months to 15 years, at the National Taiwan University Hospital, Taipei, Taiwan. Fifty-seven patients had generalized seizures (infantile spasms in 13) and 37 had focal seizures. Intravenous PLP 10 mg/kg was followed by 10 mg/kg/day orally in 4 divided doses. The dose was increased to 50 mg/kg/day if seizures recurred within 24 hours of the
doi:10.15844/pedneurbriefs-19-5-12
fatcat:7rulltm7ordjteahd5dh4vly4q