Structure and function of the Epstein-Barr virus BZLF1 protein

G Packham, A Economou, C M Rooney, D T Rowe, P J Farrell
1990 Journal of Virology  
Five DNA-binding sites for the Epstein-Barr virus BZLF1 protein have been identified within three of the early viral promoters, and four of these binding sites contain a consensus AP-1 site. The part of the BZLF1 protein required for sequence-specific DNA binding to one of these AP-1-like sites was identified by deletion mapping. Site-directed mutagenesis of this DNA target suggests that BZLF1 may work partly by overcoming a cellular repressor of viral transcription.
doi:10.1128/jvi.64.5.2110-2116.1990 fatcat:l6cbqpf2snhppfaud23cfyjfoy