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Geometry of proteins: Hydrogen bonding, sterics, and marginally compact tubes
2006
Physical Review E
The functionality of proteins is governed by their structure in the native state. Protein structures are made up of emergent building blocks of helices and almost planar sheets. A simple coarse-grained geometrical model of a flexible tube barely subject to compaction provides a unified framework for understanding the common character of globular proteins. We argue that a recent critique of the tube idea is not well founded.
doi:10.1103/physreve.73.031921
pmid:16605572
fatcat:rhwwbi5jcrbfpjcfooaurwmy5i