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Pharmacological considerations on the use of antiretrovirals in pregnancy
2013
Current Opinion in Infectious Diseases
Purpose of review Treatment with combination antiretroviral therapy during pregnancy reduces the chance of mother to child transmission of HIV. Physiological changes during pregnancy can lead to lower exposure to antiretrovirals, possibly resulting in virological failure. For most antiretrovirals, data on exposure during pregnancy and transplacental passage are limited. This review summarizes the most recent information on pharmacokinetics (including transplacental passage), efficacy, as well
doi:10.1097/qco.0000000000000017
pmid:24152762
fatcat:iruwzndxczf6tea5xmyrtdgydq