Objective: to estimate the prevalence of self-reported chronic kidney disease and associated factors in adults living in the Metropolitan Region of Manaus, Brazil. Methods: this was a population-based cross-sectional study conducted in 2015, with probabilistic sampling to select adults ≥18 years to be interviewed at home; factors associated with self-reported chronic kidney disease were investigated using hierarchical Poisson regression, to calculate prevalence ratios (PR) and 95% confidence

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... ervals (95%CI), considering the complex sampling used. Results: a total of 4,001 people were interviewed -52.8% were women, 72.2% were of brown skin color and 19.7% had hypertension; prevalence of self-reported chronic kidney disease was 2.1% (95%CI 1.6;2.5), it was positively associated with age (35-44 years old, PR=2.31, 95%CI 1.02;5.21; 45-59 years old, PR=2.52, 95%CI 1.10;5.75; ≥60 years old, PR=2.95, 95%CI 1.21;7.16) and having had strokes (PR=2.20, 95%CI 1.09;4.45). Conclusion: two out of every 100 Manaus metropolitan region inhabitants self-reported chronic kidney disease and it was more frequent in older adults and those who had had strokes.