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Proteomic approaches to uncover MMP function
2015
Matrix Biology
Proteomics has revolutionized protease research and particularly contributed to the identification of novel substrates and their sites of cleavage as key determinants of protease function. New technologies and rapid advancements in development of powerful mass spectrometers allowed unprecedented insights into activities of matrix metalloproteinases (MMPs) within their complex extracellular environments. Mass spectrometry-based proteomics extended our knowledge on MMP cleavage specificities and
doi:10.1016/j.matbio.2015.01.003
pmid:25603365
fatcat:p7tuykbrandxzl2lvd2ediv6z4