Nowadays, due to changes in the global economy (structural, technological, geopolitical) for country's competitiveness at the international level, it is necessary to digitally transform the activities of the Russian enterprises in the context of its managerial and technological processes and models, as well as enhance interaction enterprises among themselves and with other participants of the innovation system at the meso and macro levels. That is all defined as guiding lines to the achievement

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... of the scientific and technological development of the Russian Federation (The Strategy for Scientific and Technological Development of the Russian Federation on January 12, 2016, № 642). The scientific novelty of the proposed paper is to develop a theory and practical mechanisms for the transformation of managerial, technological and logistics processes at the level of individual enterprises and regional innovation systems using the latest information technology (big data analytics, cloud computing, digital twins, blockchain technology, etc.), which will ensure a drastic change in enterprise business processes and technologies for decisionmaking support. The interdisciplinary nature of the research causes introducing of new sources into scientific circulation, rethinking of scientific thought development, principles and mechanisms, as well as patterns of economic development at micro, meso, macro and global level.