Objectives: To evaluate the knowledge of the general population about the COVID-19 pandemic, including the disease and the preventive measures to reduce spreading of the virus undertaken by participants. Methods: We conducted a cross-sectional study on a Mexican population sample during the period of March 20th to March 27th in Mexico, via a computer-based survey. We evaluated general knowledge about COVID-19 and the adherence to recommendations. Results: A total of 2,577 participants completed

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... the survey. Our results revealed an overall proper knowledge about the disease, with 76.2% having the proper knowledge about the disease, which was significantly correlated with age (r=0.15, p<0.001), socioeconomic status (r=0.06, p<0.003) and maximum academic level achieved by the study subjects (r=0.12, p<0.001). Conclusions: Overall, people have good knowledge of COVID-19 and know about the specific public health recommendations, but a large proportion of people do not strictly follow these recommendations.