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Using data fusion for scoring reliability of protein–protein interactions
2014
Journal of Bioinformatics and Computational Biology
Protein-protein interactions (PPIs) are important for understanding the cellular mechanisms of biological functions, but the reliability of PPIs extracted by high-throughput assays is known to be low. To address this, many current methods use multiple evidence from di®erent sources of information to compute reliability scores for such PPIs. However, they often combine the evidence without taking into account the uncertainty of the evidence values, potential dependencies between the information
doi:10.1142/s0219720014500140
pmid:25152039
fatcat:lay45gurira4bi4gisohayloom