Eudesmane and rearranged eudesmane sesquiterpenes from Nectandra cissiflora

Fernanda R. Garcez, Walmir S. Garcez, Lidilhone Hamerski, Ana Carolina de M. Miranda
2010 Química Nova  
Recebido em 12/2/10; aceito em 6/5/10; publicado na web em 24/8/10 Four eudesmane-type sesquiterpenes, costic acid (1), 12-carboxyeudesman-3,11(13)-diene (2), viscic acid (3), 3-oxo-g-costic acid (4) and two rearranged eudesmane derivatives, 3a-hydroxyisoiphion-11(13)-en-12-oic acid (5) and 5b-hydroxy-4-oxo-11(13)dehydroiphionan-12-oic acid (6), in addition to (-)-epicatechin, have been isolated from the trunk bark of Nectandra cissiflora. This is the first reported occurrence in the Lauraceae
more » ... e in the Lauraceae of 3-6. The structures of the isolated compounds have been established on the basis of 1D and 2D NMR spectroscopic techniques. The 13 C NMR assignments of 3, 5 and 6 are given here for the first time, as well as some corrections to the previously reported chemical shift assignments of 4.
doi:10.1590/s0100-40422010000800022 fatcat:mfdss3bh5rd6fbhvyn42rfwemy