Protective Effect of Chastberrg (Vitex agnus-castus Leaves) Herbal against Nephrotoxicity on Experimental Rats

Samah A. Elsemelawy, Abeer E. Elkhamisy
2017 مجلة دراسات وبحوث التربية النوعية  
Parameters Groups Feed intake g/day/rat Body weight gain % FER Normal control 15.667±0.817 a 21.359±1.549 a 0.994±0.013 a Positive control 13.383±0.585 c 9.616±0.971 d 0.753±0.083 c 5% V. agnus-castus 14.667±0.605 b 13.988±1.496 c 0.954±0.102 b 10% V. agnus-castus 14.750±0.758 b 16.523±1.246 b 0.943±0.086 b 15 % V. agnus-castus 14.950±0.561 b 20.537±1.113 a 0.992±0.088 a Mean values in each column having different superscript letters denote significant difference.P≤0.05 Table (4): Effect of V.
more » ... gnus-castus levels on kidneys function of rats groups. Parameters Groups Uric acid mg/dl Urea Nitrogen mg/dl Creatinine mg/dl Normal group 1.93±0.042 d 31.99±2.981 d 0.94±0.054 d Positive control 2.87±0.062 a 82.98±3.577 a 4.24±0.407 a 5% V. agnus-castus 2.10±0.104 b 61.90±2.382 b 2.855±0.130 b 10% V. agnus-castus 1.91±0.126 bc 52.36±4.148 c 2.58±0.107 c 15% V. agnus-castus 1.51±0.070 c 50.26±3.338 c 2.34±0.205 c Mean values in each column having different superscript letters denote significant difference.P≤0.05 Table (5): Effect of V. agnus-castus levels on liver enzymes activity of rats groups. Parameters Groups AST Activity (Iu/l) ALT Activity (Iu/l) ALP Activity (Iu/l) Normal group 52.80±2.010 e 24.21±1.678 e 65.26±3.936 e Positive control 94.47±5.568 a 53.86±3.127 a 113.28±6.488 a 5% V. agnus-castus 70.63±4.741 b 39.76±3.013 b 90.33±3.642 b 10% V. agnus-castus 63.82±4.271 c 32.83±3.431 c 76.64±5.649 c 15% V. agnus-castus 56.92±3.022 d 27.63±2.104 d 68.96±2.622 d
doi:10.21608/jsezu.2017.238417 fatcat:odbwewcopfdvpnog464e7upueq