Premature graying of hair: An independent risk marker for coronary artery disease in smokers - A retrospective case control study
A. Aggarwal, S. Srivastava, M.P. Agarwal, S. Dwivedi
2014
Indian Heart Journal
reasons, only 5% of patients had local complications like bleeding from puncture site and hematoma at access site. Radial loops, subclavian tortuosity and arterial lusoria were encountered in a minority of patients. Radial artery patency was close to 98 percent ( as accessed by telephonic follow up). 7 years follow up of patients revealed majority of patients were doing well on medical management. Conclusion: Trans Radial outpatient diagnostic procedures can be performed with remarkable success
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... and safety with excellent long term outcome. Introduction: Dyslipidemia has been accepted as a risk factor for cardiovascular diseases and a marker of atherosclerosis. Data is scarce regarding the impact of individual lipid fractions on atherosclerosis. The present study aims to ascertain the association of individual lipid fractions on CIMT in patients presenting with coronary artery disease (CAD). Methodology: A cross sectional assessment of records of 357 patients with CAD, attending the preventive cardiology clinic in New Delhi, between 2008 and 2013 was undertaken. Details of medical history, physical examination, biochemical parameters, electrocardiograms, and CIMT measures were recorded. Results & Discussion: Of the 357 patients in this study, 84 were females, 273 were males, with a mean age of 48.6±13.17 years, of whom 61 were known diabetics and 101 had long standing hypertension. The mean CIMT (mCIMT) values for 357 individuals were 0.77±0.23 mm. With increasing age, there was an increase in mCIMT (correlation coefficient¼0.23, p<0.001). Mean TC was 153.8±39.5 mg/dl, HDL was 35.8±9.66 mg/dl, LDL was 89.9±30.6 mg/dl, TG was 135.9±80.3 mg/dl. The HDL cholesterol level was found to have a statistically significant correlation with mCIMT (coefficient¼ -0.054, p¼0.06). An increase in HDL cholesterol was associated with a decrease in mCIMT. No statistically significant correlation was found between the rest of the parameters and mCIMT. An analysis of variance done after categorizing the total cholesterol levels into <150 mg/ dl, 150-200 mg/dl, and >200 mg/dl groups showed that there was statistically significant difference in the mCIMT (p<0.05) Conclusions: Among the commonly measured lipid fractions, HDL cholesterol was found to have a statistically significant negative correlation with mCIMT, suggesting that increasing HDL cholesterol should be an important treatment goal in patients with CAD to prevent increase in CIMT which would translate into decreasing atherogenesis and cardiovascular mortality.
doi:10.1016/j.ihj.2014.10.042
fatcat:ucahypbabbdtbl2edlje3s3xc4