Bayesian spatio-temporal modelling of tobacco-related cancer data in Switzerland

Annibale Biggeri, Verena Jürgens, Jürg Utzinger, Penelope Vounatsou
2013 unpublished
Tobacco smoking is a main cause of disease in Switzerland; lung cancer being the most common cancer mortality in men and the second most common in women. Although disease-specic mortality is decreasing in men, it is steadily increasing in women. The four language regions in this country might play a role in this context as they are inuenced in dierent ways by the cultural and social behaviour of neighbouring countries. Bayesian hierarchical spatio-temporal, negative binomial models were tted on
more » ... subgroup-specic death rates indirectly standardized by national references to explore age-and gender-specic spatio-temporal patterns of mortality due to lung cancer and other tobacco-related cancers in Switzerland for the time period 19692002. Dierences inuenced by linguistic region and life in rural or urban areas were also accounted for. Male lung cancer mortality was found to be rather homogeneous in space, whereas women were conrmed to be more aected in urban regions. Compared to the German-speaking part, female mortality was higher in the French-speaking part of the country, a result contradicting other reports of similar comparisons between France and Germany. The spatio-temporal patterns of mortality were similar for lung cancer and other tobacco-related cancers. The estimated mortality maps can support the planning in health care services and evaluation of a national tobacco control programme. Better understanding of spatial and temporal variation of cancer of the lung and other tobacco-related cancers may help in allocating resources for more eective screening, diagnosis and therapy. The methodology can be applied to similar studies in other settings.
doi:10.5451/unibas-006210660 fatcat:hjc36erlarb2vlfeqvcqojycsu