In 2016, a new strategic plan is developed nationally to address the adolescent and youth health issues holistically. For its implementation, it is important to assess the available resources at health facilities. The aim of this study was to assess the readiness of the health facilities for the implementation of comprehensive adolescent and youth health care. Methods: A cross-sectional study was conducted among the youth-friendly service delivering and not delivering health facilities with 1:1

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... ratio in the central zones of Southern Nations Nationalities People Region from May 14-26, 2017. A total of 14 health centers was selected using lottery methods. The data were collected through interview and observation. Interviews were done among 14 health facility managers 14 health care providers and 5 district health office heads. Data were entered into Microsoft Excel 2010 software and descriptive analysis was made. Result: Totally, 14 health facilities were observed. Of all 42.8% of health facilities have at least six health officers, 78.5% have more than ten diploma nurses, 85.7% have diploma midwifery at least one, 70% have no displayed information items such as the rights of adolescent to information, only 50% of them have a waiting room. 75% were working in a room with no curtains in windows and doors, no screen separating the consultation area from the examination area to maintain privacy during the consultation. All health facility managers and heads of the district health office mentioned that shortage of trained manpower as a result of frequent turnover, budget, vehicle, and room were critically hampered the implementation of the services as required. Conclusion: It is possible to begin the comprehensive adolescent and youth health care service with the existing manpower health professionals and rooms. However, the training of health care providers and fulfilling the necessary medical supplies and materials are important. So, service quality will be improved based on the standards in collaboration with different stakeholders and partners.