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Cyclic AMP-Mobilizing Agents and Glucocorticoids Modulate Human Smooth Muscle Cell Migration
2003
American Journal of Respiratory Cell and Molecular Biology
Hyperplasia and cell migration of smooth muscle are features of both airway and pulmonary vascular diseases. The precise cellular and molecular mechanisms that regulate smooth muscle migration in the lungs remain unknown. In this study, we examined the effect of cAMP-mobilizing agents and steroids on smooth muscle cell migration. Platelet-derived growth factor (PDGF), transforming growth factor-␣, vascular endothelial growth factor, and basic fibroblast growth factor significantly stimulated
doi:10.1165/rcmb.2002-0254oc
pmid:12600820
fatcat:tuoyywhqingpdgsi6q6o4gygoe