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50 years of research on the phenomena and epigenetic mechanism of neurogenesis
2014
Neuroscience research
In 1960s, histological study on developing CNS led us to a novel finding that the periventricular layer ("Matrix" of W. His) of fetal neocortex is composed solely of the matrix cells. Application of 3 H-thymidine autoradiography revealed "elevator movement" of the matrix cells. Following the stage of pure matrix cell proliferation (Stage I), stage of neuron production (Stage II) ensues, and when Stage II is over, stage of gliogenesis (Stage III) follows immediately; first, glioblasts, then
doi:10.1016/j.neures.2014.10.005
pmid:24703934
fatcat:rprtf6lztje23ddwzbcnguzbti