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Circulating Cell Free DNA as Blood Based Biomarker in Breast Cancer
2015
Molecular Biology
The prevalence of circulating cell free DNA (cfDNA) in the peripheral blood of healthy persons and patients with several different diseases is well known since decades. Especially in cancer patients high amounts of cfDNA can be found because of the higher cellular turnover in cancer cells. CfDNA integrity reflects the ratio of longer to shorter DNA fragments and therefore represents the relation between non-apoptotic and apoptotic cell death. For calculation of cfDNA and cfDNA integrity
doi:10.4172/2168-9547.1000120
fatcat:ee2m4k54brdcvmm5w2ja3bzehy