Challenges and limitations of quantifying brain connectivityin vivowith diffusion MRI

Derek K Jones
2010 Imaging in Medicine  
pERSpECTIVE Challenges and limitations of quantifying brain connectivity in vivo with diffusion MRI of diffusion MRI and fiber tracking is given and the early applications of diffusion MRI to study connectivity are reviewed. A close and critical inspection is then made of the limitations inherent in these different approaches, challenging the notion that it is possible to quantify brain connectivity in vivo with diffusion MRI. Finally, steps toward improving quantification of connectivity, by
more » ... tegrating information from other techniques, are suggested.
doi:10.2217/iim.10.21 fatcat:hjfoxhms4rautkiws5hxol634a