A Comparison of Donor-Acceptor Distance Distributions Derived from Ensemble and Single-Pair FRET Measurements

Tanya A. Baldwin, Gi-Ho Kim, Tyrel R. Deutscher, Maria E. Moutsoglou, John M. Robinson
2012 Biophysical Journal  
evolve on three different timescales during the 240-minute observation window during folding, and are interpreted in terms of pore formation, bilayer traversal, and equilibration in the membrane. These results augment the existing models that describe concerted insertion and folding events, and highlight the ability of FRET to provide insight into the complex mechanisms of membrane protein folding.
doi:10.1016/j.bpj.2011.11.2201 fatcat:ijd3s5cvwnag7bado3zfzmoza4