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Some fifty years in the development of ideas about the definition and use of functional regions are elaborated in this article, as an introduction to this Special Issue of the Moravian Geographical Reports. The conceptual basis for functional regions is discussed, initially in relation to region-organising interactions and their behavioural foundations. This paper presents an approach to functional regions which presumes that such regions objectively exist and that they are based on more ordoi:10.1515/mgr-2016-0006 fatcat:vdgc5yel6jeklclavboqykx5ja