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In this study we investigated a simple nonlabor-intensive method to evaluate insulin sensitivity and p-cell function which is suitable for application in population studies. The method is a refinement of the modified Harano test and consists of a continuous low dose insulin (25 mU/kgh) and glucose (4 mg/kg.min) infusion test (LDIGIT) lasting 150 min. Insulin sensitivity was evaluated as the MCR of glucose divided by the steady state serum insulin level achieved at the end of the test. Insulindoi:10.1210/jc.80.1.34 pmid:7829636 fatcat:bhl4rjeudrdsxm4mrtixs3fifi