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Recent insights into oocyte - follicle cell interactions provide opportunities for the development of new approaches to in vitro maturation
2011
Reproduction, Fertility and Development
The last 5-10 years of research in ovarian and oocyte biology has delivered some major new advances in knowledge of the molecular and cellular processes regulating oocyte maturation and oocyte developmental competence. These new insights include, among others: (1) the knowledge that oocytes regulate granulosa and cumulus cell differentiation, ovulation rate and fertility via the secretion of soluble paracrine growth factors; (2) new perspectives on the participation of cyclic nucleotides,
doi:10.1071/rd10225
pmid:21366977
fatcat:gnbs44rbivgr5crjmq2qor6koy