Impact Genetic Characterization of H5N1 Avian Influenza Virus Isolated from Dead Mute Swan (Cygnus Olor)

Bogoyavlenskiy Andrey, Korotetskiy Ilya, Turmagambetova Aizhan, Prilipov Alexey, Abitayeva Madina, Soldatova Irina, Berezin Vladimir
2012 Journal of Virology and Microbiology  
and aim: The influenza viruses pose a threat of emergence of a global pandemic influenza through point mutation or reassortment, leading to a strain that can effectively transmit among humans. In this study, the authors present phylogenetic and genetic evidences for the interlineage reassortment among avian influenza viruses isolated in Kazakhstan in 2006 from a mute swan. Methods: This study demonstrates the dynamic nature of the influenza virus genes pool in Eurasia with continuing gene
more » ... ges between the eastern and western parts of the continent. Results: The findings suggest that the H5N1 -like virus were likely derived directly from viruses resident in migratory birds. Conclusion: The failure to identify the source of all gene segments of A/mute swan/Aktau/1460/06 virus and its variant highlights the need of continued and extensive surveillance in both migratory and domestic populations of birds in large regions. Such surveillance is crucial for efficient pandemic influenza preparedness.
doi:10.5171/2012.256191 fatcat:lasbzgbpmzaavjthufsab2rsvi