Sarcoidosis Accompanied by Systemic Lupus Erythematosus and Autoimmune Hepatitis

Seiko Nakayama, Hiroshi Mukae, Tomohito Morisaki, Noriho Sakamoto, Kazuo Ohba, Koh Abe, Fuminao Takeshima, Yohei Mizuta, Hiroaki Ida, Yoshiyuki Ozono, Shigeru Kohno
2007 Internal medicine (Tokyo. 1992)  
A 52-year-old woman was admitted to our hospital for further examination of blurred vision, abnormal lung shadows and an elevated level of angiotensin-converting enzyme. Sarcoidosis was suspected, however, careful history taking revealed the existence of photosensitivity and polyarthralgia. Laboratory tests showed lymphocytopenia, liver dysfunction, hypergammaglobulinemia, and positive anti-nuclear, anti-double stranded DNA and anti-smooth muscle antibodies. Liver biopsy examination showed
more » ... ic active hepatitis. She was diagnosed with the triplex of sarcoidosis, systemic lupus erythematosus and autoimmune hepatitis. Marked improvement was noted after corticosteroid therapy. 23: 364-366, 1980. 4. Needleman SW, Silber RA, Von Brecht JH, Goeeken JA. Systemic lupus erythematosus complicated by disseminated sarcoidosis. Report of a case associated with circulating immune complexes. Am J Clin Pathol 78: 105-107, 1982. 5. Aronson PJ, Fretzin DF, Morgan NE. A unique case of sarcoidosis with coexistent collagen vascular disease. Possible result of a compatible disease-sustaining immunologic environment. J Am 2007 The Japanese Society of Internal Medicine
doi:10.2169/internalmedicine.46.0201 pmid:17917329 fatcat:5nnyopxgn5ehhai5vyeohp2ylq