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Emergent oscillations during cellular directional decision-making on junctions
Motile cells inside living tissues often encounter junctions, where their path branches into several alternative directions of migration. We present a theoretical model of cellular polarization for cells migrating along one-dimensional lines, arriving at a symmetric Y-junction and extending protrusions along the different paths that emanate from the junction. The model predicts the spontaneous emergence of deterministic oscillations between competing protrusions, whereby the cellulardoi:10.1101/2022.10.14.512239 fatcat:ag4mxocl5rhglfdljcddnt23uu