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Optical interrogation of sympathetic neuronal effects on macroscopic cardiomyocyte network dynamics
2020
iScience
Cardiac stimulation via sympathetic neurons can potentially trigger arrhythmias. We present approaches to study neuron-cardiomyocyte interactions involving optogenetic selective probing and all-optical electrophysiology to measure activity in an automated fashion. Here we demonstrate the utility of optical interrogation of sympathetic neurons and their effects on macroscopic cardiomyocyte network dynamics to address research targets such as the effects of adrenergic stimulation via the release
doi:10.1016/j.isci.2020.101334
pmid:32674058
pmcid:PMC7363704
fatcat:nksjqzw6hrf2xa5vrn4p25azva