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Allele-specific expression analysis methods for high-density SNP microarray data
2012
Bioinformatics
Motivation: In the past decade, a number of technologies to quantify allele-specific expression (ASE) in a genome-wide manner have become available to researchers. We investigate the application of SNP microarrays to this task, exploring data obtained from both celllines and primary tissue for which both RNA and DNA profiles are available. Results: We analyze data from two experiments that make use of high-density Illumina Infinium II genotyping arrays to measure ASE. We first preprocess each
doi:10.1093/bioinformatics/bts089
pmid:22355082
fatcat:pnyzpoohmvghplvnuvb7cogc4u