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A Cellular System for Spatial Signal Decoding in Chemical Gradients
2015
Developmental Cell
Graphical Abstract Highlights d The site of polarity establishment is selected independently of gradient direction d A mobile polarity complex is guided toward the gradient prior to polarized growth d Site mobility requires restricting Cdc42 activity through Cdc24 nuclear sequestration d Fus3 sets Cdc24 sequestration to switch from site mobility to polarized growth SUMMARY Directional cell growth requires that cells read and interpret shallow chemical gradients, but how the gradient directional
doi:10.1016/j.devcel.2015.10.013
pmid:26585298
fatcat:7oyjinomavhh5kabbkmla7y2wa