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The F, generation hybrids of carp and goldfish exhibited a marked hyperplasia of pars distalis basophil (gonadotrophic) cells, which first became evident in 3-to 4-year-old fish, the age at which carp and goldfish normally become sexually mature. Many of these hybrids also developed gonadal tumors, the genesis of which also coincided with the onset of gonadotroph proliferation. In these fish the baso phil hyperplasia was more marked than in nontumorous hy brids. Tumor-bearing carp alsopmid:884668 fatcat:zi2mopk7vnejrhbni6axbxg2jy