IgA Nephropathy Associated with Portal Hypertension in Liver Cirrhosis due to Non-Alcoholic and Non-A, Non-B, Non-C Hepatitis

Mono NAKAMURA, Akira OHISHI, Reiko WATANABE, Kohtaro KANEKO, Noboru AOSAKI, Tomohiko IIGAYA, Tetsuo MONMA, Hitoshi SUGIURA, Yukari MIYOSHI, Kinichi HAMAGUCHI
1994 Internal medicine (Tokyo. 1992)  
A 69-year-old female was admitted to our hospital because of leg edema, proteinuria (2.1 g/ day), and gross hematuria. She had non-alcoholic liver cirrhosis of unknown etiology. Esophageal varices also were found. Examination of the renal biopsy specimen revealed mesangial proliferative glomerulonephritis with IgA deposits. Propranolol was administered orally to reduce portal hypertension, resulting in a progressive decrease in urinary microalbumin excretion. This case suggests that portal
more » ... tension is involved in the pathogenesis of IgA nephropathy in liver cirrhosis. (Internal Medicine 33: 488-491, 1994)
doi:10.2169/internalmedicine.33.488 fatcat:6tt6yg6olfba7dwksj5frse54q