Correlation structure of end-expiratory lung volume in anesthetized rats with intact upper airway

Xiaobin Zhang, Eugene N. Bruce
2000 American Journal of Physiology. Regulatory Integrative and Comparative Physiology  
Zhang, Xiaobin, and Eugene N. Bruce. Correlation structure of end-expiratory lung volume in anesthetized rats with intact upper airway. Am J Physiol Regulatory Integrative Comp Physiol 278: R1446-R1452, 2000.-The correlation structure of breath-to-breath fluctuations of end-expiratory lung volume (EEV) was studied in anesthetized rats with intact airways subjected to positive and negative transrespiratory pressure (i.e., PTRP and NTRP, correspondingly). The Hurst exponent, H, was estimated from
more » ... was estimated from EEV fluctuations using modified dispersional analysis. We found that H for EEV was 0.5362 Ϯ 0.0763 and 0.6403 Ϯ 0.0561 with PTRP and NTRP, respectively (mean Ϯ SD). Both H were significantly different from those obtained after random shuffling of the original time series. Also, H with NTRP was significantly greater than that with PTRP (P ϭ 0.029). We conclude that in rats breathing through the upper airway, a positive long-term correlation is present in EEV that is different between PTRP and NTRP.
doi:10.1152/ajpregu.2000.278.6.r1446 pmid:10848510 fatcat:tepu6l7ylrdwrmreyx7hiikpxu