Влияние длительности заболевания на развитие кардиальной патологии при анкилозирующем спондилите
Influence of the duration of the disease on the development of the cardial pathology in anklosing spondilitis

2019 Dalʹnevostočnyj medicinskij žurnal  
Ankylosing spondylitis (AS) is a disease characterized by a lesion not only of the musculoskeletal system, but also of the internal organs, including the heart. Objective: to identify the relationship between the duration of the disease and cardiac pathology in patients with AS. Material and methods: the study involved 85 patients with AS, which divided into two groups depending on the duration of the disease at the time of diagnosis and initiation of treatment. Group 1 – with duration of the
more » ... h duration of the disease less than 3 years (51 people). Group 2 – with duration of the disease more than 3 years (34 people). Indices of ASDAS-ESR, BASDAI, BASFI, echocardiographic parameters (left ventricular mass index, relative thickness of ventricular wall, E/a of mitral and tricuspid valves) and indicators of vectorcardiography (areas of loops P, QRS and T, MV-voltage, MV-azimuth, MV-rise) were calculated. The results showed that in patients with ankylosing spondylitis lasting up to 3 years there is a tendency to the development of left ventricular diastolic dysfunction and a decrease in the electrical activity of the left heart. With the increase in the duration of the disease, we found a tendency to the development of diastolic dysfunction of the right ventricle, also accompanied by an increase in the proportion of electrically inactive myocardium.
doi:10.35177/1994-5191-2019-3-21-23 fatcat:b5gz6fdksbhgzdjawvzpdbkkse