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Resistance to anticancer vaccination effect is controlled by a cancer cell-autonomous phenotype that disrupts immunogenic phagocytic removal
2015
OncoTarget
Immunogenic cell death (ICD) is a well-established instigator of 'anti-cancer vaccination-effect (AVE)' . ICD has shown considerable preclinical promise, yet there remain subset of cancer patients that fail to respond to clinically-applied ICD inducers. Non-responsiveness to ICD inducers could be explained by the existence of cancer cell-autonomous, anti-AVE resistance mechanisms. However such resistance mechanisms remain poorly investigated. In this study, we have characterized for the first
doi:10.18632/oncotarget.4754
pmid:26314964
pmcid:PMC4694957
fatcat:iqzmbq3x5vevbavgp6yrx3dwtq