Skin cancer is common nowadays. Early diagnosis of skin cancer is essential to increase patients' survival rate. In addition to traditional methods, computer-aided diagnosis is used in diagnosis of skin cancer. One of the benefits of this method is that it eliminates human error in cancer diagnosis. Skin images may contain noise such as like hair, ink spots, rulers, etc., in addition to the lesion. For this reason, noise removal is required. The noise reduction in lesion images can be referred

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... o as noise removal. This phase is very important for the correct segmentation of the lesions. One of the most critical problems in using such automated methods is the inaccuracy in cancer diagnosis because noise removal and segmentation cannot be performed effectively. We have created a noise dataset (hair, rulers, ink spots, etc.) that includes 2500 images and masks. There is no such noise dataset in the literature. We used this dataset for noise removal in skin cancer images. Two datasets from the International Skin Imaging Collaboration (ISIC) and the PH2 were used in this study. In this study, a new approach called LinkNet-B7 for noise removal and segmentation of skin cancer images is presented. LinkNet-B7 is a LinkNet-based approach that uses EfficientNetB7 as the encoder. We used images with 16 slices. This way, we lose fewer pixel values. LinkNet-B7 has a 6% higher success rate than LinkNet with the same dataset and parameters. Training accuracy for noise removal and lesion segmentation was calculated to be 95.72% and 97.80%, respectively.