CHRONIC PRURITUS IN CHILD'S SKIN DISEASES
Хронічний свербіж при захворюваннях шкіри в дітей

L.D. Kaliuzhna, Shupyk National Medical Academy of Postgraduate Education
2020 Dermatology and Venerology  
The article presents modern information on the clinical use and safety of the first-generation H1-antihistamine – dimetindene maleate. Pruritus (itch) mediators act both peripherally (histamine, proteases) and centrally (opioids) and has several mechanisms. Pruritus is the dominant symptom of skin diseases; almost all inflamamatory skin diseases can have associated pruritus. Doctors have focused on the almost one dermatosis with signs of itching – atopic dermatitis. At the same time, the range
more » ... f diseases, both dermatological and systemic, accompanied by itching, is much wider.
doi:10.33743/2308-1066-2020-3-29-32 fatcat:gxs2dq7aa5ce3bwl5ykgxdp2fi