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Functional Characterization of Porcine (Sus scrofa) BCL10
Open Journal of Immunology
Human BCL10 (hBCL10) protein is a signal transduction molecule originally identified because of its direct involvement in a subset of mucosa-associated lymphoid tissue (MALT) lymphomas, and later recognized as a crucial factor in regulating activation of NF-kB transcription factor following antigen receptor stimulation on lymphocytes. In this study, we characterized the NF-kB inducing activity of porcine BCL10 (pBCL10). pBCL10 oligimerizes, binds to components of the CARMA/ BCL10/MALT1 complexdoi:10.4236/oji.2015.52007 fatcat:ka3qzluaq5eulp57j6i7s5n524