Assessment of anti-hyperlipidemic effect of Citrullus colocynthis

Marzyieh Zamani, Alireza O. Rahimi, Reza Mahdavi, Mohammed Nikbakhsh, Morteza V. Jabbari, Hassan Rezazadeh, Abbas Delazar, Lutfun Nahar, Satyajit D. Sarker
2007 Revista Brasileira de Farmacognosia  
RESUMO: "Avaliação do efeito antihiperlipidêmico de Citrullus colocynthis". Hiperlipidemia é um fator de risco bem conhecido para diversas doenças inclusive aterosclerose, doenças cardíacas e derrame cerebral. Na procura de potenciais agentes antihiperlipidêmicos a partir de plantas para prevenir essas doenças, a polpa e as sementes de Citrullus colocynthis foram testadas para verifi car seus efeitos no perfi l lipídico de coelhos Nova Zelândia hiperlipidêmicos. Nos grupos experimentais que
more » ... perimentais que receberam a polpa de C. colocynthis ou 100 mg/kg das sementes, os perfi s lipídicos foram signifi cantemente reduzidos quando comparados ao grupo de controle (P<0,05). ABSTRACT: Hyperlipidemia is a well-known risk factor for several illnesses including atherosclerosis, heart and vascular diseases and stroke. In the search for potential antihyperlipidemic agents from plants to prevent these conditions, the pulp and the seeds of Citrullus colocynthis were assessed for their effects on the lipid profi le of hyperlipidemic New Zealand rabbits. In the experimental groups that received the pulp of C. colocynthis or 100 mg/kg of seeds, the lipid profi les were signifi cantly reduced when compared to the control group (P<0.05). Assessment of anti-hyperlipidemic effect of Citrullus colocynthis Rev. Bras. Farmacogn. Braz J. Pharmacogn. 17(4): Out./Dez. 2007 Marzyieh Zamani, Alireza O. Rahimi, Reza Mahdavi, et al. Rev. Bras. Farmacogn. Braz J. Pharmacogn. 17(4): Out./Dez. 2007
doi:10.1590/s0102-695x2007000400003 fatcat:25laer6serax5pdvry6opq3s2a