Personalized Medicine and Genomics: Challenges and Opportunities in Assessing Effectiveness, Cost-Effectiveness, and Future Research Priorities

Rena Conti, David L. Veenstra, Katrina Armstrong, Lawrence J. Lesko, Scott D. Grosse
2010 Medical decision making  
Personalized medicine is health care that tailors interventions to individual variation in risk and treatment response. Although medicine has long strived to achieve this goal, advances in genomics promise to facilitate this process. Relevant to present-day practice is the use of genomic information to classify individuals according to disease susceptibility or expected responsiveness to a pharmacologic treatment and to provide targeted interventions. A symposium at the annual meeting of the
more » ... iety for Medical Decision Making on 23 October 2007 highlighted the challenges and opportunities posed in translating advances in molecular medicine into clinical practice. A panel of US experts in medical practice, regulatory policy, technology assessment, and the financing and organization of medical innovation was asked to discuss the current state of
doi:10.1177/0272989x09347014 pmid:20086232 pmcid:PMC4598076 fatcat:i4rpdnjrerfitd2uxdwvtkc6em