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MicroRNAs (miRNAs/miRs) have been implicated in the development and progression of osteosarcoma. miR-448 is emerging as a tumor-associated miRNA in many human cancers. However, the role of miR-448 in osteosarcoma remains unknown. The present study aimed to identify the potential role of miR-448 in osteosarcoma. It was demonstrated that miR-448 was significantly downregulated in osteosarcoma cell lines, as detected by reverse transcription-quantitative polymerase chain reaction (RT-qPCR).doi:10.3892/mmr.2017.7249 pmid:28849015 fatcat:milksogpdfdodnwkh7voitszy4