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Cardiovascular Responses Induced by Catalase Inhibitior into the Fourth Cerebral Ventricle Is Changed in Wistar Rats Exposed to Sidestream Cigarette Smoke
International Journal of Health Sciences
Objectives: This experimental study aimed to evaluate the effects of central catalase inhibition on cardiovascular responses in rats exposed to sidestream cigarette smoke (SSCS) for 3 weeks. Methodology: A total of 20 males Wistar rats (320-370g) were implanted with a stainless steel guide cannula into the fourth cerebral ventricle (4 th V). Femoral artery and vein were cannulated for mean arterial pressure (MAP) and heart rate (HR) measurement and drug infusion, respectively. Rats were exposeddoi:10.12816/0006043 fatcat:fsuhtfk7cvbgfiiwozgimd7zwm